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A Protective Role of the NRF2-Keap1 Pathway in Maintaining Intestinal Barrier Function

Nrf2 (NF-E2-related factor 2) is a master regulator of cellular oxidative levels against environmental stresses. Nrf2 induces the expression of metabolic detoxification and antioxidant enzymes to eliminate reactive oxygen species (ROS). The gastrointestinal tract is a key source of ROS. Intestinal b...

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Detalles Bibliográficos
Autores principales: Wen, Zhiyong, Liu, Weihua, Li, Xing, Chen, Weiguo, Liu, Zhice, Wen, Jianbo, Liu, Zhiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617875/
https://www.ncbi.nlm.nih.gov/pubmed/31346356
http://dx.doi.org/10.1155/2019/1759149