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The engineering principles of combining a transcriptional incoherent feedforward loop with negative feedback
BACKGROUND: Regulation of gene expression is of paramount importance in all living systems. In the past two decades, it has been discovered that certain motifs, such as the feedforward motif, are overrepresented in gene regulatory circuits. Feedforward loops are also ubiquitous in process control en...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617889/ https://www.ncbi.nlm.nih.gov/pubmed/31333758 http://dx.doi.org/10.1186/s13036-019-0190-3 |