T cells expressing NKG2D chimeric antigen receptors efficiently eliminate glioblastoma and cancer stem cells

BACKGROUND: Traditional therapies fail to cure most glioblastoma patients and the 5-year survival rate is less than 10%, highlighting need for new therapeutic approaches. The natural killer group 2 member D ligands (NKG2DLs) are highly expressed in glioblastomas and are considered promising targets...

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Detalles Bibliográficos
Autores principales: Yang, Dong, Sun, Bin, Dai, Hongjiu, Li, Wenxuan, Shi, Lan, Zhang, Peixian, Li, Shirong, Zhao, Xudong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617951/
https://www.ncbi.nlm.nih.gov/pubmed/31288857
http://dx.doi.org/10.1186/s40425-019-0642-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617951/
https://www.ncbi.nlm.nih.gov/pubmed/31288857
http://dx.doi.org/10.1186/s40425-019-0642-9

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