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T cells expressing NKG2D chimeric antigen receptors efficiently eliminate glioblastoma and cancer stem cells
BACKGROUND: Traditional therapies fail to cure most glioblastoma patients and the 5-year survival rate is less than 10%, highlighting need for new therapeutic approaches. The natural killer group 2 member D ligands (NKG2DLs) are highly expressed in glioblastomas and are considered promising targets...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617951/ https://www.ncbi.nlm.nih.gov/pubmed/31288857 http://dx.doi.org/10.1186/s40425-019-0642-9 |