Cargando…

The plasmid‐borne quinolone resistance protein QnrB, a novel DnaA‐binding protein, increases the bacterial mutation rate by triggering DNA replication stress

Bacterial antibiotic resistance, a global health threat, is caused by plasmid transfer or genetic mutations. Quinolones are important antibiotics, partially because they are fully synthetic and resistance genes are unlikely to exist in nature; nonetheless, quinolone resistance proteins have been ide...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Xiaojing, Zhang, Yujiao, Zhou, Xintong, Hu, Xinling, Zhou, Yixuan, Liu, Di, Maxwell, Anthony, Mi, Kaixia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617969/
https://www.ncbi.nlm.nih.gov/pubmed/30838726
http://dx.doi.org/10.1111/mmi.14235