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Peripheral IgE Repertoires of Healthy Donors Carry Moderate Mutation Loads and Do Not Overlap With Other Isotypes
IgE-mediated allergic disease represents an increasing health problem. Although numerous studies have investigated IgE sequences in allergic patients, little information is available on the healthy IgE repertoire. IgM, IgG, IgA, and IgE transcripts from peripheral blood B cells of five healthy, non-...
Autores principales: | Koning, Marvyn T., Trollmann, Ignis J. M., van Bergen, Cornelis A. M., Alvarez Saravia, Diego, Navarrete, Marcelo A., Kiełbasa, Szymon M., Veelken, Hendrik |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617986/ https://www.ncbi.nlm.nih.gov/pubmed/31333671 http://dx.doi.org/10.3389/fimmu.2019.01543 |
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