Tumor mutational burden standardization initiatives: Recommendations for consistent tumor mutational burden assessment in clinical samples to guide immunotherapy treatment decisions

Characterization of tumors utilizing next‐generation sequencing methods, including assessment of the number of somatic mutations (tumor mutational burden [TMB]), is currently at the forefront of the field of personalized medicine. Recent clinical studies have associated high TMB with improved patien...

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Detalles Bibliográficos
Autores principales: Stenzinger, Albrecht, Allen, Jeffrey D., Maas, Jörg, Stewart, Mark D., Merino, Diana M., Wempe, Madison M., Dietel, Manfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6618007/
https://www.ncbi.nlm.nih.gov/pubmed/30664300
http://dx.doi.org/10.1002/gcc.22733

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6618007/
https://www.ncbi.nlm.nih.gov/pubmed/30664300
http://dx.doi.org/10.1002/gcc.22733

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