Protein kinase A‐mediated phosphorylation of naked cuticle homolog 2 stimulates cell‐surface delivery of transforming growth factor‐α for epidermal growth factor receptor transactivation

The classic mode of G protein‐coupled receptor (GPCR)‐mediated transactivation of the receptor tyrosine kinase epidermal growth factor receptor (EGFR) transactivation occurs via matrix metalloprotease (MMP)‐mediated cleavage of plasma membrane‐anchored EGFR ligands. Herein, we show that the Gαs‐acti...

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Detalles Bibliográficos
Autores principales: Cao, Zheng, Singh, Bhuminder, Li, Cunxi, Markham, Nicholas O., Carrington, Léolène J., Franklin, Jeffrey L., Graves‐Deal, Ramona, Kennedy, Eileen J., Goldenring, James R., Coffey, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons A/S 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6618044/
https://www.ncbi.nlm.nih.gov/pubmed/30941853
http://dx.doi.org/10.1111/tra.12642

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6618044/
https://www.ncbi.nlm.nih.gov/pubmed/30941853
http://dx.doi.org/10.1111/tra.12642

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