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Sustained‐release of sclerostin single‐chain antibody fragments using poly(lactic‐co‐glycolic acid) microspheres for osteoporotic fracture repair
Osteoporotic fracture is one of the most common bone diseases in middle and old age, as the most serious consequence of osteoporosis. Sclerostin single‐chain antibody fragments (SCL‐scFv) have been proven to promote bone formation by binding to scleroprotein, a natural antagonist of the Wnt pathway,...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6618085/ https://www.ncbi.nlm.nih.gov/pubmed/31012249 http://dx.doi.org/10.1002/jbm.a.36704 |