Determinants of Cytochrome P450 2D6 mRNA Levels in Healthy Human Liver Tissue

Cytochrome P450 2D6 (CYP2D6) is a major drug‐metabolizing enzyme that exhibits large interindividual variability. Recent studies suggest that differential transcriptional regulation of CYP2D6 in part may be responsible for the variability. In this study, we characterized potential determinants of CY...

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Detalles Bibliográficos
Autores principales: Ning, Miaoran, Duarte, Julio D., Stevison, Faith, Isoherranen, Nina, Rubin, Leah H., Jeong, Hyunyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6618095/
https://www.ncbi.nlm.nih.gov/pubmed/30821899
http://dx.doi.org/10.1111/cts.12632

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6618095/
https://www.ncbi.nlm.nih.gov/pubmed/30821899
http://dx.doi.org/10.1111/cts.12632

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