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Astrocyte‐specific deletion of the mitochondrial m‐AAA protease reveals glial contribution to neurodegeneration
Mitochondrial dysfunction causes neurodegeneration but whether impairment of mitochondrial homeostasis in astrocytes contributes to this pathological process remains largely unknown. The m‐AAA protease exerts quality control and regulatory functions crucial for mitochondrial homeostasis. AFG3L2, whi...
Autores principales: | Murru, Sara, Hess, Simon, Barth, Esther, Almajan, Eva R., Schatton, Désirée, Hermans, Steffen, Brodesser, Susanne, Langer, Thomas, Kloppenburg, Peter, Rugarli, Elena I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6618114/ https://www.ncbi.nlm.nih.gov/pubmed/30989755 http://dx.doi.org/10.1002/glia.23626 |
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