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A combination pharmacotherapy of tapentadol and pregabalin to tackle centrally driven osteoarthritis pain

BACKGROUND: Many Osteoarthritis (OA) patients report with clinical features to their pain that cannot be explained by purely peripheral mechanisms. Yet, the analgesic agents available that tackle centrally driven chronic pain often provide only partial pain relief, or have dose‐limiting side effects...

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Detalles Bibliográficos
Autores principales: Lockwood, Stevie Margaret, Dickenson, Anthony H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6618140/
https://www.ncbi.nlm.nih.gov/pubmed/30821870
http://dx.doi.org/10.1002/ejp.1386