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Induction of a Four‐Way Junction Structure in the DNA Palindromic Hexanucleotide 5′‐d(CGTACG)‐3′ by a Mononuclear Platinum Complex

Four‐way junctions (4WJs) are supramolecular DNA assemblies comprising four interacting DNA strands that in biology are involved in DNA‐damage repair. In this study, a new mononuclear platinum(II) complex 1 was prepared that is capable of driving the crystallization of the DNA oligomer 5′‐d(CGTACG)‐...

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Detalles Bibliográficos
Autores principales: van Rixel, Vincent H. S., Busemann, Anja, Wissingh, Mathijs F., Hopkins, Samantha L., Siewert, Bianka, van de Griend, Corjan, Siegler, Maxime A., Marzo, Tiziano, Papi, Francesco, Ferraroni, Marta, Gratteri, Paola, Bazzicalupi, Carla, Messori, Luigi, Bonnet, Sylvestre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6618160/
https://www.ncbi.nlm.nih.gov/pubmed/31046177
http://dx.doi.org/10.1002/anie.201814532