Alteration of the Route to Menaquinone towards Isochorismate‐Derived Metabolites

Chorismate and isochorismate constitute branch‐point intermediates in the biosynthesis of many aromatic metabolites in microorganisms and plants. To obtain unnatural compounds, we modified the route to menaquinone in Escherichia coli. We propose a model for the binding of isochorismate to the active...

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Detalles Bibliográficos
Autores principales: Fries, Alexander, Mazzaferro, Laura S., Grüning, Björn, Bisel, Philippe, Stibal, Karin, Buchholz, Patrick C. F., Pleiss, Jürgen, Sprenger, Georg A., Müller, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6618250/
https://www.ncbi.nlm.nih.gov/pubmed/30866142
http://dx.doi.org/10.1002/cbic.201900050

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6618250/
https://www.ncbi.nlm.nih.gov/pubmed/30866142
http://dx.doi.org/10.1002/cbic.201900050

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