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IL‐2 therapy preferentially expands adoptively transferred donor‐specific Tregs improving skin allograft survival

Regulatory T cells (Tregs) have unique immunosuppressive properties and are essential to ensure effective immunoregulation. In animal models, Tregs have been shown to prevent autoimmune disorders and establish transplantation tolerance. Therefore, the prospect of harnessing Tregs, either by increasi...

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Detalles Bibliográficos
Autores principales: Ratnasothy, Kulachelvy, Jacob, Jacintha, Tung, Sim, Boardman, Dominic, Lechler, Robert Ian, Sanchez-Fueyo, Alberto, Martinez‐Llordella, Marc, Lombardi, Giovanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6618286/
https://www.ncbi.nlm.nih.gov/pubmed/30748096
http://dx.doi.org/10.1111/ajt.15306