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IL‐2 therapy preferentially expands adoptively transferred donor‐specific Tregs improving skin allograft survival
Regulatory T cells (Tregs) have unique immunosuppressive properties and are essential to ensure effective immunoregulation. In animal models, Tregs have been shown to prevent autoimmune disorders and establish transplantation tolerance. Therefore, the prospect of harnessing Tregs, either by increasi...
Autores principales: | Ratnasothy, Kulachelvy, Jacob, Jacintha, Tung, Sim, Boardman, Dominic, Lechler, Robert Ian, Sanchez-Fueyo, Alberto, Martinez‐Llordella, Marc, Lombardi, Giovanna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6618286/ https://www.ncbi.nlm.nih.gov/pubmed/30748096 http://dx.doi.org/10.1111/ajt.15306 |
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