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Pharmacokinetics and Safety of CSL112 (Apolipoprotein A‐I [Human]) in Adults With Moderate Renal Impairment and Normal Renal Function

CSL112 (Apolipoprotein A‐I [human]) is an intravenous preparation of apolipoprotein A‐I (apoA‐I), formulated with phosphatidylcholine (PC) and stabilized with sucrose, in development to prevent early recurrent cardiovascular events following acute myocardial infarction (AMI). This phase 1 study was...

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Detalles Bibliográficos
Autores principales: Tortorici, Michael A., Duffy, Danielle, Evans, Rebecca, Feaster, John, Gille, Andreas, Mant, Timothy G. K., Wright, Samuel D., D'Andrea, Denise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6618313/
https://www.ncbi.nlm.nih.gov/pubmed/30240132
http://dx.doi.org/10.1002/cpdd.618