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MicroRNA-149 Suppresses Inflammation in Nucleus Pulposus Cells of Intervertebral Discs by Regulating MyD88

BACKGROUND: Intervertebral disc degeneration (IDD) is associated with low back and neck pain, but the mechanisms underlying its pathogenesis are unclear. In this study, we explored the function of microRNA-149 (miR-149) in inflammatory response mediated by lipopolysaccharide (LPS) in nucleus pulposu...

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Detalles Bibliográficos
Autores principales: Qin, Chuqiang, Lv, Yuming, Zhao, Hongpu, Yang, Bo, Zhang, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6618342/
https://www.ncbi.nlm.nih.gov/pubmed/31263091
http://dx.doi.org/10.12659/MSM.915858