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Sustained effectiveness, safety and therapeutic drug monitoring of tioguanine in a cohort of 274 IBD patients intolerant for conventional therapies

BACKGROUND: Tioguanine (or thioguanine) is an alternative drug for IBD patients who fail prior conventional immunomodulating therapy. AIM: To report effectiveness, safety and therapeutic drug monitoring in a cohort of patients with prolonged tioguanine maintenance therapy. METHODS: In this nationwid...

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Detalles Bibliográficos
Autores principales: Simsek, Melek, Deben, Debbie S., Horjus, Carmen S., Bénard, Melanie V., Lissenberg‐Witte, Birgit I., Buiter, Hans J. C., van Luin, Matthijs, Seinen, Margien L., Mulder, Chris J. J., Wong, Dennis R., de Boer, Nanne K. H., van Bodegraven, Adriaan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6618772/
https://www.ncbi.nlm.nih.gov/pubmed/31094013
http://dx.doi.org/10.1111/apt.15280