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Aged human skin accumulates mast cells with altered functionality that localize to macrophages and vasoactive intestinal peptide‐positive nerve fibres

BACKGROUND: Skin health declines with age and this is partially attributed to immunosenescence. Mast cells (MCs) are innate immune cells that coordinate tissue immune responses integral to skin homeostasis and disease. OBJECTIVES: To understand how MCs contribute to human skin ageing, we investigate...

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Detalles Bibliográficos
Autores principales: Pilkington, S.M., Barron, M.J., Watson, R.E.B., Griffiths, C.E.M., Bulfone‐Paus, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6619242/
https://www.ncbi.nlm.nih.gov/pubmed/30291626
http://dx.doi.org/10.1111/bjd.17268