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Radiosynthesis of the norepinephrine transporter tracer [(18)F]NS12137 via copper‐mediated (18) F‐labelling

[(18)F]NS12137 (exo‐3‐[(6‐[(18)F]fluoro‐2‐pyridyl)oxy]8‐azabicyclo[3.2.1]octane) is a highly selective norepinephrine transporter (NET) tracer. NETs are responsible for the reuptake of norepinephrine and dopamine and are linked to several neurodegenerative and neuropsychiatric disorders. The aim of...

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Detalles Bibliográficos
Autores principales: Lahdenpohja, Salla, Keller, Thomas, Rajander, Johan, Kirjavainen, Anna K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6619244/
https://www.ncbi.nlm.nih.gov/pubmed/30843249
http://dx.doi.org/10.1002/jlcr.3717