Enhanced Microbial Bile Acid Deconjugation and Impaired Ileal Uptake in Pregnancy Repress Intestinal Regulation of Bile Acid Synthesis

Pregnancy is associated with progressive hypercholanemia, hypercholesterolemia, and hypertriglyceridemia, which can result in metabolic disease in susceptible women. Gut signals modify hepatic homeostatic pathways, linking intestinal content to metabolic activity. We sought to identify whether enter...

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Detalles Bibliográficos
Autores principales: Ovadia, Caroline, Perdones‐Montero, Alvaro, Spagou, Konstantina, Smith, Ann, Sarafian, Magali H., Gomez‐Romero, Maria, Bellafante, Elena, Clarke, Louise C.D., Sadiq, Fouzia, Nikolova, Vanya, Mitchell, Alice, Dixon, Peter H., Santa‐Pinter, Natalie, Wahlström, Annika, Abu‐Hayyeh, Shadi, Walters, Julian R.F., Marschall, Hanns‐Ulrich, Holmes, Elaine, Marchesi, Julian R., Williamson, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6619257/
https://www.ncbi.nlm.nih.gov/pubmed/30983011
http://dx.doi.org/10.1002/hep.30661

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6619257/
https://www.ncbi.nlm.nih.gov/pubmed/30983011
http://dx.doi.org/10.1002/hep.30661

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