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Gain of FGF4 is a frequent event in KIT/PDGFRA/SDH/RAS‐P WT GIST

Gastrointestinal stromal tumors (GIST) lacking mutations in KIT/PDGFRA or RAS pathways and retaining an intact SDH complex are usually referred to as KIT/PDGFRA/SDH/RAS‐P WT GIST or more simply quadruple WT GIST (~5% of all GIST). Despite efforts made, no recurrent genetic event in quadruple WT GIST...

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Detalles Bibliográficos
Autores principales: Urbini, Milena, Indio, Valentina, Tarantino, Giuseppe, Ravegnini, Gloria, Angelini, Sabrina, Nannini, Margherita, Saponara, Maristella, Santini, Donatella, Ceccarelli, Claudio, Fiorentino, Michelangelo, Vincenzi, Bruno, Fumagalli, Elena, Casali, Paolo Giovanni, Grignani, Giovanni, Pession, Andrea, Ardizzoni, Andrea, Astolfi, Annalisa, Pantaleo, Maria Abbondanza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6619263/
https://www.ncbi.nlm.nih.gov/pubmed/30887595
http://dx.doi.org/10.1002/gcc.22753