On the differences between mega‐ and meta‐imputation and analysis exemplified on the genetics of age‐related macular degeneration

While current genome‐wide association analyses often rely on meta‐analysis of study‐specific summary statistics, individual participant data (IPD) from multiple studies increase options for modeling. When multistudy IPD is available, however, it is unclear whether this data is to be imputed and mode...

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Detalles Bibliográficos
Autores principales: Gorski, Mathias, Günther, Felix, Winkler, Thomas W., Weber, Bernhard H. F., Heid, Iris M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6619271/
https://www.ncbi.nlm.nih.gov/pubmed/31016765
http://dx.doi.org/10.1002/gepi.22204

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6619271/
https://www.ncbi.nlm.nih.gov/pubmed/31016765
http://dx.doi.org/10.1002/gepi.22204

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