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On the differences between mega‐ and meta‐imputation and analysis exemplified on the genetics of age‐related macular degeneration
While current genome‐wide association analyses often rely on meta‐analysis of study‐specific summary statistics, individual participant data (IPD) from multiple studies increase options for modeling. When multistudy IPD is available, however, it is unclear whether this data is to be imputed and mode...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6619271/ https://www.ncbi.nlm.nih.gov/pubmed/31016765 http://dx.doi.org/10.1002/gepi.22204 |