Enrichment of fetal and maternal long cell‐free DNA fragments from maternal plasma following DNA repair

OBJECTIVE: Cell‐free DNA (cfDNA) fragments in maternal plasma contain DNA damage and may negatively impact the sensitivity of noninvasive prenatal testing (NIPT). However, some of these DNA damages are potentially reparable. We aimed to recover these damaged cfDNA molecules using PreCR DNA repair mi...

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Detalles Bibliográficos
Autores principales: Vong, Joaquim S.L., Jiang, Peiyong, Cheng, Suk‐Hang, Lee, Wing‐Shan, Tsang, Jason C.H., Leung, Tak‐Yeung, Chan, K.C. Allen, Chiu, Rossa W.K., Lo, Y.M. Dennis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6619283/
https://www.ncbi.nlm.nih.gov/pubmed/30575063
http://dx.doi.org/10.1002/pd.5406

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6619283/
https://www.ncbi.nlm.nih.gov/pubmed/30575063
http://dx.doi.org/10.1002/pd.5406

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