Minimizing the Entropy Penalty for Ligand Binding: Lessons from the Molecular Recognition of the Histo Blood‐Group Antigens by Human Galectin‐3

Ligand conformational entropy plays an important role in carbohydrate recognition events. Glycans are characterized by intrinsic flexibility around the glycosidic linkages, thus in most cases, loss of conformational entropy of the sugar upon complex formation strongly affects the entropy of the bind...

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Detalles Bibliográficos
Autores principales: Gimeno, Ana, Delgado, Sandra, Valverde, Pablo, Bertuzzi, Sara, Berbís, Manuel Alvaro, Echavarren, Javier, Lacetera, Alessandra, Martín‐Santamaría, Sonsoles, Surolia, Avadhesha, Cañada, Francisco Javier, Jiménez‐Barbero, Jesus, Ardá, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6619289/
https://www.ncbi.nlm.nih.gov/pubmed/30942512
http://dx.doi.org/10.1002/anie.201900723

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6619289/
https://www.ncbi.nlm.nih.gov/pubmed/30942512
http://dx.doi.org/10.1002/anie.201900723

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