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Lipids as Trans-Acting Effectors for α-Synuclein in the Pathogenesis of Parkinson’s Disease

Aggregation of α-synuclein (αSyn) plays a central role in the pathogenesis of Parkinson’s disease (PD) and dementia with Lewy bodies (DLB). Lewy bodies (LBs) and Lewy neurites, which consist mainly of aggregated αSyn, are widely observed in the affected regions of patient brains. Except for some fam...

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Detalles Bibliográficos
Autores principales: Ikenaka, Kensuke, Suzuki, Mari, Mochizuki, Hideki, Nagai, Yoshitaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6619337/
https://www.ncbi.nlm.nih.gov/pubmed/31333408
http://dx.doi.org/10.3389/fnins.2019.00693