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Estimating and testing direct genetic effects in directed acyclic graphs using estimating equations
In genetic association studies, it is important to distinguish direct and indirect genetic effects in order to build truly functional models. For this purpose, we consider a directed acyclic graph setting with genetic variants, primary and intermediate phenotypes, and confounding factors. In order t...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6619348/ https://www.ncbi.nlm.nih.gov/pubmed/29265408 http://dx.doi.org/10.1002/gepi.22107 |