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Estimating and testing direct genetic effects in directed acyclic graphs using estimating equations

In genetic association studies, it is important to distinguish direct and indirect genetic effects in order to build truly functional models. For this purpose, we consider a directed acyclic graph setting with genetic variants, primary and intermediate phenotypes, and confounding factors. In order t...

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Detalles Bibliográficos
Autores principales: Konigorski, Stefan, Wang, Yuan, Cigsar, Candemir, Yilmaz, Yildiz E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6619348/
https://www.ncbi.nlm.nih.gov/pubmed/29265408
http://dx.doi.org/10.1002/gepi.22107