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ELK1 has a dual activating and repressive role in human embryonic stem cells

Background: The ERK MAPK pathway plays a pivotal role in regulating numerous cellular processes during normal development and in the adult but is often deregulated in disease scenarios. One of its key nuclear targets is the transcription factor ELK1, which has been shown to play an important role in...

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Detalles Bibliográficos
Autores principales: Prise, Ian, Sharrocks, Andrew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6619381/
https://www.ncbi.nlm.nih.gov/pubmed/31346550
http://dx.doi.org/10.12688/wellcomeopenres.15091.2