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A Distinct Pool of Na(v)1.5 Channels at the Lateral Membrane of Murine Ventricular Cardiomyocytes

Background: In cardiac ventricular muscle cells, the presence of voltage-gated sodium channels Na(v)1.5 at the lateral membrane depends in part on the interaction between the dystrophin–syntrophin complex and the Na(v)1.5 C-terminal PDZ-domain-binding sequence Ser-Ile-Val (SIV motif). α1-Syntrophin,...

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Detalles Bibliográficos
Autores principales: Rougier, Jean-Sébastien, Essers, Maria C., Gillet, Ludovic, Guichard, Sabrina, Sonntag, Stephan, Shmerling, Doron, Abriel, Hugues
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6619393/
https://www.ncbi.nlm.nih.gov/pubmed/31333492
http://dx.doi.org/10.3389/fphys.2019.00834