Cargando…

A Distinct Pool of Na(v)1.5 Channels at the Lateral Membrane of Murine Ventricular Cardiomyocytes

Background: In cardiac ventricular muscle cells, the presence of voltage-gated sodium channels Na(v)1.5 at the lateral membrane depends in part on the interaction between the dystrophin–syntrophin complex and the Na(v)1.5 C-terminal PDZ-domain-binding sequence Ser-Ile-Val (SIV motif). α1-Syntrophin,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rougier, Jean-Sébastien, Essers, Maria C., Gillet, Ludovic, Guichard, Sabrina, Sonntag, Stephan, Shmerling, Doron, Abriel, Hugues
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6619393/ https://www.ncbi.nlm.nih.gov/pubmed/31333492 http://dx.doi.org/10.3389/fphys.2019.00834

Ejemplares similares

Dystrophin and calcium current are decreased in cardiomyocytes expressing Cre enzyme driven by αMHC but not TNT promoter
por: Gillet, Ludovic, et al.
Publicado: (2019)

Transcriptomic analyses of murine ventricular cardiomyocytes
por: Chevalier, Morgan, et al.
Publicado: (2018)

Corrigendum: Transcriptomic analyses of murine ventricular cardiomyocytes
por: Chevalier, Morgan, et al.
Publicado: (2018)

Deletion of Trpm4 Alters the Function of the Na(v)1.5 Channel in Murine Cardiac Myocytes
por: Ozhathil, Lijo Cherian, et al.
Publicado: (2021)

Knockdown of the TRPM4 channel alters cardiac electrophysiology and hemodynamics in a sex‐ and age‐dependent manner in mice
por: Arullampalam, Prakash, et al.
Publicado: (2023)

Proteasome inhibitor (MG132) rescues Na(v)1.5 protein content and the cardiac sodium current in dystrophin-deficient mdx(5cv) mice
por: Rougier, Jean-Sébastien, et al.
Publicado: (2013)

Electrophysiological properties of mouse and epitope-tagged human cardiac sodium channel Na (v)1.5 expressed in HEK293 cells
por: Reinhard, Katja, et al.
Publicado: (2013)

Single-Molecule Localization of the Cardiac Voltage-Gated Sodium Channel Reveals Different Modes of Reorganization at Cardiomyocyte Membrane Domains
por: Vermij, Sarah H., et al.
Publicado: (2020)

Glycosylation of TRPM4 and TRPM5 channels: molecular determinants and functional aspects
por: Syam, Ninda, et al.
Publicado: (2014)

Neuronal Precursor Cell-expressed Developmentally Down-regulated 4-1 (NEDD4-1) Controls the Sorting of Newly Synthesized Ca(V)1.2 Calcium Channels
por: Rougier, Jean-Sebastien, et al.
Publicado: (2011)

Functional implications of a rare variant in the sodium channel β1B subunit (SCN1B) in a 5-month-old male sudden infant death syndrome case
por: Neubauer, Jacqueline, et al.
Publicado: (2018)

Calmodulin binds to the N-terminal domain of the cardiac sodium channel Na(v)1.5
por: Wang, Zizun, et al.
Publicado: (2020)

Ubiquitin-specific protease USP2-45 acts as a molecular switch to promote α(2)δ-1-induced downregulation of Ca(v)1.2 channels
por: Rougier, Jean-Sebastien, et al.
Publicado: (2014)

Species-Specific Effects of Cation Channel TRPM4 Small-Molecule Inhibitors
por: Arullampalam, Prakash, et al.
Publicado: (2021)

Reduced cardiomyocyte Na(+) current in the age‐dependent murine Pgc‐1β (−/−) model of ventricular arrhythmia
por: Ahmad, Shiraz, et al.
Publicado: (2018)

Biophysical Characterization of Epigallocatechin-3-Gallate Effect on the Cardiac Sodium Channel Na(v)1.5
por: Amarouch, Mohamed-Yassine, et al.
Publicado: (2020)

The ion channel TRPM4 in murine experimental autoimmune encephalomyelitis and in a model of glutamate-induced neuronal degeneration
por: Bianchi, Beatrice, et al.
Publicado: (2018)

Testing the Cre-mediated genetic switch for the generation of conditional knock-in mice
por: Capulli, Mattia, et al.
Publicado: (2019)

Two functionally distinct pools of glycosaminoglycan in the substrate adhesion site of murine cells
Publicado: (1978)

Annotation of functional impact of voltage‐gated sodium channel mutations
por: Hinard, Valérie, et al.
Publicado: (2017)

Channel Openings Are Necessary but not Sufficient for Use-dependent Block of Cardiac Na(+) Channels by Flecainide: Evidence from the Analysis of Disease-linked Mutations
por: Liu, Huajun, et al.
Publicado: (2002)

Mepivacaine reduces calcium transients in isolated murine ventricular cardiomyocytes
por: Mosqueira, Matias, et al.
Publicado: (2020)

Specific decreasing of Na(+) channel expression on the lateral membrane of cardiomyocytes causes fatal arrhythmias in Brugada syndrome
por: Tsumoto, Kunichika, et al.
Publicado: (2020)

β1- and β3- voltage-gated sodium channel subunits modulate cell surface expression and glycosylation of Na(v)1.7 in HEK293 cells
por: Laedermann, Cédric J., et al.
Publicado: (2013)

Na(+)-induced Ca(2+) influx through reverse mode of Na(+)-Ca(2+) exchanger in mouse ventricular cardiomyocyte
por: Yan, Zhen-Yu, et al.
Publicado: (2015)

Editorial: Inherited Arrhythmias of the Cardiac Sodium Channel Na(v)1.5
por: Amarouch, Mohamed-Yassine, et al.
Publicado: (2021)

Distinctive electrophysiological characteristics of right ventricular out-flow tract cardiomyocytes
por: Lu, Yen-Yu, et al.
Publicado: (2014)

Gnathodiaphyseal dysplasia is not recapitulated in a respective mouse model carrying a mutation of the Ano5 gene
por: Rolvien, Tim, et al.
Publicado: (2020)

Variable Na(v)1.5 Protein Expression from the Wild-Type Allele Correlates with the Penetrance of Cardiac Conduction Disease in the Scn5a (+/−) Mouse Model
por: Leoni, Anne-Laure, et al.
Publicado: (2010)

Absence of Functional Na(v)1.8 Channels in Non-diseased Atrial and Ventricular Cardiomyocytes
por: Casini, Simona, et al.
Publicado: (2020)

Load-dependent effects of apelin on murine cardiomyocytes
por: Peyronnet, Rémi, et al.
Publicado: (2017)

Piezo2 is not an indispensable mechanosensor in murine cardiomyocytes
por: Kloth, Benjamin, et al.
Publicado: (2022)

ICEPO: the ion channel electrophysiology ontology
por: Hinard, V., et al.
Publicado: (2016)

Distinct α2 Na,K-ATPase membrane pools are differently involved in early skeletal muscle remodeling during disuse
por: Kravtsova, Violetta V., et al.
Publicado: (2016)

Cardiomyocyte Na(+)/H(+) Exchanger-1 Activity Is Reduced in Hypoxia
por: Kandilci, Hilmi Burak, et al.
Publicado: (2021)

Prevalence of Significant Genetic Variants in Congenital Long QT Syndrome is Largely Underestimated
por: Zaklyazminskaya, Elena V., et al.
Publicado: (2012)

Cellular hyper-excitability caused by mutations that alter the activation process of voltage-gated sodium channels
por: Amarouch, Mohamed-Yassine, et al.
Publicado: (2015)

Variants of Transient Receptor Potential Melastatin Member 4 in Childhood Atrioventricular Block
por: Syam, Ninda, et al.
Publicado: (2016)

Functional Consequences of the SCN5A-p.Y1977N Mutation within the PY Ubiquitylation Motif: Discrepancy between HEK293 Cells and Transgenic Mice
por: Casini, Simona, et al.
Publicado: (2019)

Dietary Mg(2+) Intake and the Na(+)/Mg(2+) Exchanger SLC41A1 Influence Components of Mitochondrial Energetics in Murine Cardiomyocytes
por: Tatarkova, Zuzana, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_e0sf119ortagafvge8bdu9p39v