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Characterization of Serotonin Signaling Components in Patients with Inflammatory Bowel Disease

BACKGROUND: Tryptophan hydroxylase (TPH)1 catalyzes the biosynthesis of serotonin (5-hydroxytrptamine; 5-HT) in enterochromaffin (EC) cells, the predominant source of gut 5-HT. Secreted 5-HT regulates various gut functions through diverse 5-HT receptor (5-HTR) families, and 5-HT transporter (5-HTT)...

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Detalles Bibliográficos
Autores principales: Shajib, Md Sharif, Chauhan, Usha, Adeeb, Salman, Chetty, Yeshale, Armstrong, David, Halder, Smita L S, Marshall, John K, Khan, Waliul I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6619411/
https://www.ncbi.nlm.nih.gov/pubmed/31294376
http://dx.doi.org/10.1093/jcag/gwy039