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Single-Cell Glia and Neuron Gene Expression in the Central Amygdala in Opioid Withdrawal Suggests Inflammation With Correlated Gut Dysbiosis

Drug-seeking in opioid dependence is due in part to the severe negative emotion associated with the withdrawal syndrome. It is well-established that negative emotional states emerge from activity in the amygdala. More recently, gut microflora have been shown to contribute substantially to such emoti...

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Detalles Bibliográficos
Autores principales: O’Sullivan, Sean J., Malahias, Evangelia, Park, James, Srivastava, Ankita, Reyes, Beverly A. S., Gorky, Jon, Vadigepalli, Rajanikanth, Van Bockstaele, Elisabeth J., Schwaber, James S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6619439/
https://www.ncbi.nlm.nih.gov/pubmed/31333398
http://dx.doi.org/10.3389/fnins.2019.00665