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MeCP2 Deficiency Disrupts Kainate-Induced Presynaptic Plasticity in the Mossy Fiber Projections in the Hippocampus

Methyl cytosine binding protein 2 (MeCP2) is a structural chromosomal protein involved in the regulation of gene expression. Mutations in the gene encoding MeCP2 result in Rett Syndrome (RTT), a pervasive neurodevelopmental disorder. RTT is one of few autism spectrum disorders whose cause was identi...

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Detalles Bibliográficos
Autores principales: Bertoldi, Maria Laura, Zalosnik, Maria Ines, Fabio, Maria Carolina, Aja, Susan, Roth, German A., Ronnett, Gabriele V., Degano, Alicia L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6619486/
https://www.ncbi.nlm.nih.gov/pubmed/31333414
http://dx.doi.org/10.3389/fncel.2019.00286