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Caenorhabditis elegans hub genes that respond to amyloid beta are homologs of genes involved in human Alzheimer’s disease

The prominent characteristic of Alzheimer’s disease (AD) is the accumulation of amyloid beta (Abeta) proteins in the form of plaques that cause molecular and cellular alterations in the brain. Due to the paucity of brain samples of early-stage Abeta aggregation, animal models have been developed to...

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Detalles Bibliográficos
Autores principales: Godini, Rasoul, Pocock, Roger, Fallahi, Hossein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6619800/
https://www.ncbi.nlm.nih.gov/pubmed/31291334
http://dx.doi.org/10.1371/journal.pone.0219486