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Acute myeloid leukemia immunopeptidome reveals HLA presentation of mutated nucleophosmin

Somatic mutations in cancer are a potential source of cancer specific neoantigens. Acute myeloid leukemia (AML) has common recurrent mutations shared between patients in addition to private mutations specific to individuals. We hypothesized that neoantigens derived from recurrent shared mutations wo...

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Detalles Bibliográficos
Autores principales: Narayan, Rupa, Olsson, Niclas, Wagar, Lisa E., Medeiros, Bruno C., Meyer, Everett, Czerwinski, Debra, Khodadoust, Michael S., Zhang, Lichao, Schultz, Liora, Davis, Mark M., Elias, Joshua E., Levy, Ron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6619824/
https://www.ncbi.nlm.nih.gov/pubmed/31291378
http://dx.doi.org/10.1371/journal.pone.0219547