Clonal expansion of SIV-infected cells in macaques on antiretroviral therapy is similar to that of HIV-infected cells in humans

Clonal expansion of HIV infected cells plays an important role in the formation and persistence of the reservoir that allows the virus to persist, in DNA form, despite effective antiretroviral therapy. We used integration site analysis to ask if there is a similar clonal expansion of SIV infected ce...

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Detalles Bibliográficos
Autores principales: Ferris, Andrea L., Wells, David W., Guo, Shuang, Del Prete, Gregory Q., Swanstrom, Adrienne E., Coffin, John M., Wu, Xiaolin, Lifson, Jeffrey D., Hughes, Stephen H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6619828/
https://www.ncbi.nlm.nih.gov/pubmed/31291371
http://dx.doi.org/10.1371/journal.ppat.1007869

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6619828/
https://www.ncbi.nlm.nih.gov/pubmed/31291371
http://dx.doi.org/10.1371/journal.ppat.1007869

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