Cargando…

Clonal expansion of SIV-infected cells in macaques on antiretroviral therapy is similar to that of HIV-infected cells in humans

Clonal expansion of HIV infected cells plays an important role in the formation and persistence of the reservoir that allows the virus to persist, in DNA form, despite effective antiretroviral therapy. We used integration site analysis to ask if there is a similar clonal expansion of SIV infected ce...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ferris, Andrea L., Wells, David W., Guo, Shuang, Del Prete, Gregory Q., Swanstrom, Adrienne E., Coffin, John M., Wu, Xiaolin, Lifson, Jeffrey D., Hughes, Stephen H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6619828/ https://www.ncbi.nlm.nih.gov/pubmed/31291371 http://dx.doi.org/10.1371/journal.ppat.1007869

Ejemplares similares

Host Immunity to Mycobacterium tuberculosis Infection Is Similar in Simian Immunodeficiency Virus (SIV)-Infected, Antiretroviral Therapy-Treated and SIV-Naïve Juvenile Macaques
por: Larson, Erica C., et al.
Publicado: (2023)

Experimental colitis in SIV-uninfected rhesus macaques recapitulates important features of pathogenic SIV infection
por: Hao, Xing Pei, et al.
Publicado: (2015)

Gammaherpesvirus infection and malignant disease in rhesus macaques experimentally infected with SIV or SHIV
por: Marshall, Vickie A., et al.
Publicado: (2018)

Neuroinflammatory Profiling in SIV-Infected Chinese-Origin Rhesus Macaques on Antiretroviral Therapy
por: Solis-Leal, Antonio, et al.
Publicado: (2022)

Antiretroviral therapy restores the homeostatic state of microglia in SIV‐infected rhesus macaques
por: Trease, Andrew J., et al.
Publicado: (2022)

Interleukin-10 contributes to reservoir establishment and persistence in SIV-infected macaques treated with antiretroviral therapy
por: Harper, Justin, et al.
Publicado: (2022)

Tissue viral dynamics in SIV infected macaques with highly active antiretroviral therapy (HAART)
por: Bourry, Olivier, et al.
Publicado: (2009)

Butyrate administration is not sufficient to improve immune reconstitution in antiretroviral-treated SIV-infected macaques
por: Ortiz, Alexandra M., et al.
Publicado: (2022)

Plasmodium infection reduces the volume of the viral reservoir in SIV-infected rhesus macaques receiving antiretroviral therapy
por: Zhan, Xiao-Yong, et al.
Publicado: (2014)

Clonal Expansion of Infected CD4+ T Cells in People Living with HIV
por: Coffin, John M., et al.
Publicado: (2021)

Effects of Treatment with Suppressive Combination Antiretroviral Drug Therapy and the Histone Deacetylase Inhibitor Suberoylanilide Hydroxamic Acid; (SAHA) on SIV-Infected Chinese Rhesus Macaques
por: Ling, Binhua, et al.
Publicado: (2014)

Transient viral replication during analytical treatment interruptions in SIV infected macaques can alter the rebound-competent viral reservoir
por: Immonen, Taina T., et al.
Publicado: (2021)

Cytotoxic Capacity of SIV-Specific CD8(+) T Cells against Primary Autologous Targets Correlates with Immune Control in SIV-Infected Rhesus Macaques
por: Mendoza, Daniel, et al.
Publicado: (2013)

Clinical monitoring and correlates of nephropathy in SIV-infected macaques during high-dose antiretroviral therapy
por: Sanders-Beer, Brigitte E, et al.
Publicado: (2011)

Loss of tetherin antagonism by Nef impairs SIV replication during acute infection of rhesus macaques
por: Tavakoli-Tameh, Aidin, et al.
Publicado: (2020)

Distinct Phenotype, Longitudinal Changes of Numbers and Cell-Associated Virus in Blood Dendritic Cells in SIV-Infected CD8-Lymphocyte Depleted Macaques
por: Soulas, Caroline, et al.
Publicado: (2015)

Early Loss of Splenic Tfh Cells in SIV-Infected Rhesus Macaques
por: Moukambi, Félicien, et al.
Publicado: (2015)

SIV Infection Facilitates Mycobacterium tuberculosis Infection of Rhesus Macaques
por: Guo, Ming, et al.
Publicado: (2017)

Alterations of the gut bacterial microbiota in rhesus macaques with SIV infection and on short- or long-term antiretroviral therapy
por: Siddiqui, Summer, et al.
Publicado: (2020)

Prolonged Antiretroviral Treatment Induces Adipose Tissue Remodelling Associated with Mild Inflammation in SIV-Infected Macaques
por: Mausoléo, Aude, et al.
Publicado: (2022)

SIV Evolutionary Dynamics in Cynomolgus Macaques during SIV-Mycobacterium tuberculosis Co-Infection
por: Tisthammer, Kaho H., et al.
Publicado: (2021)

Increased neutrophil apoptosis in chronically SIV-infected macaques
por: Elbim, Carole, et al.
Publicado: (2009)

MHC and KIR Polymorphisms in Rhesus Macaque SIV Infection
por: Walter, Lutz, et al.
Publicado: (2015)

Collapse of Cytolytic Potential in SIV-Specific CD8+ T Cells Following Acute SIV Infection in Rhesus Macaques
por: Roberts, Emily R., et al.
Publicado: (2016)

Similar Impact of CD8+ T Cell Responses on Early Virus Dynamics during SIV Infections of Rhesus Macaques and Sooty Mangabeys
por: Kouyos, Roger D., et al.
Publicado: (2010)

Persistent Viral Reservoirs in Lymphoid Tissues in SIV-Infected Rhesus Macaques of Chinese-Origin on Suppressive Antiretroviral Therapy
por: Siddiqui, Summer, et al.
Publicado: (2019)

Liver Bacterial Dysbiosis With Non-Tuberculosis Mycobacteria Occurs in SIV-Infected Macaques and Persists During Antiretroviral Therapy
por: Fisher, Bridget S., et al.
Publicado: (2022)

Viral dissemination and immune activation modulate antiretroviral drug levels in lymph nodes of SIV-infected rhesus macaques
por: Srinivasula, Sharat, et al.
Publicado: (2023)

Correction: Early Loss of Splenic Tfh Cells in SIV-Infected Rhesus Macaques
por: Moukambi, Félicien, et al.
Publicado: (2016)

Evaluation of Functional NK Cell Responses in Vaccinated and SIV-Infected Rhesus Macaques
por: Vargas-Inchaustegui, Diego A., et al.
Publicado: (2016)

Semen CD4(+) T Cells and Macrophages Are Productively Infected at All Stages of SIV infection in Macaques
por: Bernard-Stoecklin, Sibylle, et al.
Publicado: (2013)

IL-2 immunotherapy in chronically SIV-infected Rhesus Macaques
por: Garibal, Julie, et al.
Publicado: (2012)

Rhesus macaque IFITM3 gene polymorphisms and SIV infection
por: Winkler, Michael, et al.
Publicado: (2017)

Cynomolgus macaque IL37 polymorphism and control of SIV infection
por: Shiina, Takashi, et al.
Publicado: (2019)

Predictors of SIV recrudescence following antiretroviral treatment interruption
por: Pinkevych, Mykola, et al.
Publicado: (2019)

Limited impact of fingolimod treatment during the initial weeks of ART in SIV-infected rhesus macaques
por: Pino, Maria, et al.
Publicado: (2022)

Isolation and Characterization of Intestinal Epithelial Cells from Normal and SIV-Infected Rhesus Macaques
por: Pan, Diganta, et al.
Publicado: (2012)

Biologically-Directed Modeling Reflects Cytolytic Clearance of SIV-Infected Cells In Vivo in Macaques
por: Wick, W. David, et al.
Publicado: (2012)

CD4 Depletion in SIV-Infected Macaques Results in Macrophage and Microglia Infection with Rapid Turnover of Infected Cells
por: Micci, Luca, et al.
Publicado: (2014)

Experimental Oral Herpes Simplex Virus-1 (HSV-1) Co-infection in Simian Immunodeficiency Virus (SIV)-Infected Rhesus Macaques
por: Aravantinou, Meropi, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_mb45pbe6povkqtc53jqo0rjm3j