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Fasting prevents hypoxia-induced defects of proteostasis in C. elegans
Low oxygen conditions (hypoxia) can impair essential physiological processes and cause cellular damage and death. We have shown that specific hypoxic conditions disrupt protein homeostasis in C. elegans, leading to protein aggregation and proteotoxicity. Here, we show that nutritional cues regulate...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6619831/ https://www.ncbi.nlm.nih.gov/pubmed/31246952 http://dx.doi.org/10.1371/journal.pgen.1008242 |