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Fasting prevents hypoxia-induced defects of proteostasis in C. elegans

Low oxygen conditions (hypoxia) can impair essential physiological processes and cause cellular damage and death. We have shown that specific hypoxic conditions disrupt protein homeostasis in C. elegans, leading to protein aggregation and proteotoxicity. Here, we show that nutritional cues regulate...

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Detalles Bibliográficos
Autores principales: Iranon, Nicole N., Jochim, Bailey E., Miller, Dana L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6619831/
https://www.ncbi.nlm.nih.gov/pubmed/31246952
http://dx.doi.org/10.1371/journal.pgen.1008242