Cyclin-Specific Docking Mechanisms Reveal the Complexity of M-CDK Function in the Cell Cycle

Cyclin-dependent kinases (CDKs) coordinate hundreds of molecular events during the cell cycle. Multiple cyclins are involved, but the global role of cyclin-specific phosphorylation has remained unsolved. We uncovered a cyclin docking motif, LxF, that mediates binding of replication factor Cdc6 to mi...

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Detalles Bibliográficos
Autores principales: Örd, Mihkel, Venta, Rainis, Möll, Kaidi, Valk, Ervin, Loog, Mart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6620034/
https://www.ncbi.nlm.nih.gov/pubmed/31101497
http://dx.doi.org/10.1016/j.molcel.2019.04.026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6620034/
https://www.ncbi.nlm.nih.gov/pubmed/31101497
http://dx.doi.org/10.1016/j.molcel.2019.04.026

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