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Cyclin-Specific Docking Mechanisms Reveal the Complexity of M-CDK Function in the Cell Cycle
Cyclin-dependent kinases (CDKs) coordinate hundreds of molecular events during the cell cycle. Multiple cyclins are involved, but the global role of cyclin-specific phosphorylation has remained unsolved. We uncovered a cyclin docking motif, LxF, that mediates binding of replication factor Cdc6 to mi...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6620034/ https://www.ncbi.nlm.nih.gov/pubmed/31101497 http://dx.doi.org/10.1016/j.molcel.2019.04.026 |