Examining the involvement of Slx5 in the apoptotic response to chronic activation of the spindle assembly checkpoint

Microtubule-targeting agents represent one of the most successful groups of anticancer drugs used in cancer therapy today. These drugs induce a prolonged mitotic arrest through chronic spindle assembly checkpoint (SAC) activation. Apoptosis, an outcome of the prolonged mitotic arrest, is the main me...

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Detalles Bibliográficos
Autores principales: ATALAY, Pınar Buket, ÇAVUŞOĞLU, Elif Ergin, AŞCI, Öykü, AYGÜNEŞ, Duygu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Scientific and Technological Research Council of Turkey 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6620037/
https://www.ncbi.nlm.nih.gov/pubmed/31320817
http://dx.doi.org/10.3906/biy-1812-46

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6620037/
https://www.ncbi.nlm.nih.gov/pubmed/31320817
http://dx.doi.org/10.3906/biy-1812-46

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