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Examining the involvement of Slx5 in the apoptotic response to chronic activation of the spindle assembly checkpoint
Microtubule-targeting agents represent one of the most successful groups of anticancer drugs used in cancer therapy today. These drugs induce a prolonged mitotic arrest through chronic spindle assembly checkpoint (SAC) activation. Apoptosis, an outcome of the prolonged mitotic arrest, is the main me...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Scientific and Technological Research Council of Turkey
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6620037/ https://www.ncbi.nlm.nih.gov/pubmed/31320817 http://dx.doi.org/10.3906/biy-1812-46 |