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Squalene attenuates the oxidative stress and activates AKT/mTOR pathway against cisplatin-induced kidney damage in mice

The clinical use of cisplatin, which is a first-line anticancer agent, is highly restricted due to its adverse effects on kidneys that lead to nephrotoxicity. Therefore, some potential reno-protective substances have been used in combination with cisplatin to cope with nephrotoxicity. Due to its hig...

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Detalles Bibliográficos
Autores principales: SAKUL, Arzu, OZANSOY, Mehmet, ELİBOL, Birsen, AYLA, Şule, GÜNAL, Mehmet Yalçın, YOZGAT, Yasemin, BAŞAĞA, Hüveyda, ŞAHİN, Kazım, KAZANCIOĞLU, Rümeyza, KILIÇ, Ülkan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Scientific and Technological Research Council of Turkey 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6620038/
https://www.ncbi.nlm.nih.gov/pubmed/31320816
http://dx.doi.org/10.3906/biy-1902-77