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The C-terminal tail of the bacterial translocation ATPase SecA modulates its activity

In bacteria, the translocation of proteins across the cytoplasmic membrane by the Sec machinery requires the ATPase SecA. SecA binds ribosomes and recognises nascent substrate proteins, but the molecular mechanism of nascent substrate recognition is unknown. We investigated the role of the C-termina...

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Detalles Bibliográficos
Autores principales: Jamshad, Mohammed, Knowles, Timothy J, White, Scott A, Ward, Douglas G, Mohammed, Fiyaz, Rahman, Kazi Fahmida, Wynne, Max, Hughes, Gareth W, Kramer, Günter, Bukau, Bernd, Huber, Damon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6620043/
https://www.ncbi.nlm.nih.gov/pubmed/31246174
http://dx.doi.org/10.7554/eLife.48385