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Nerve injury drives a heightened state of vigilance and neuropathic sensitization in Drosophila

Injury can lead to devastating and often untreatable chronic pain. While acute pain perception (nociception) evolved more than 500 million years ago, virtually nothing is known about the molecular origin of chronic pain. Here we provide the first evidence that nerve injury leads to chronic neuropath...

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Detalles Bibliográficos
Autores principales: Khuong, Thang M., Wang, Qiao-Ping, Manion, John, Oyston, Lisa J., Lau, Man-Tat, Towler, Harry, Lin, Yong Qi, Neely, G. Gregory
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6620091/
https://www.ncbi.nlm.nih.gov/pubmed/31309148
http://dx.doi.org/10.1126/sciadv.aaw4099