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Altered distribution, aggregation, and protease resistance of cellular prion protein following intracranial inoculation
Prion protein (PrP(C)) is a protease-sensitive and soluble cell surface glycoprotein expressed in almost all mammalian cell types. PrP(Sc), a protease-resistant and insoluble form of PrP(C), is the causative agent of prion diseases, fatal and transmissible neurogenerative diseases of mammals. Prion...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6620108/ https://www.ncbi.nlm.nih.gov/pubmed/31291644 http://dx.doi.org/10.1371/journal.pone.0219457 |