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Altered distribution, aggregation, and protease resistance of cellular prion protein following intracranial inoculation

Prion protein (PrP(C)) is a protease-sensitive and soluble cell surface glycoprotein expressed in almost all mammalian cell types. PrP(Sc), a protease-resistant and insoluble form of PrP(C), is the causative agent of prion diseases, fatal and transmissible neurogenerative diseases of mammals. Prion...

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Detalles Bibliográficos
Autores principales:	Ward, Anne, Hollister, Jason R., Choi, Young Pyo, Race, Brent, Williams, Katie, Shoup, Daniel W., Moore, Roger A., Priola, Suzette A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6620108/ https://www.ncbi.nlm.nih.gov/pubmed/31291644 http://dx.doi.org/10.1371/journal.pone.0219457

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