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Integrative multi-omic analysis identifies new drivers and pathways in molecularly distinct subtypes of ALS

Amyotrophic lateral sclerosis (ALS) is an incurable and fatal neurodegenerative disease. Increasing the chances of success for future clinical strategies requires more in-depth knowledge of the molecular basis underlying disease heterogeneity. We recently laid the foundation for a molecular taxonomy...

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Detalles Bibliográficos
Autores principales: Morello, Giovanna, Guarnaccia, Maria, Spampinato, Antonio Gianmaria, Salomone, Salvatore, D’Agata, Velia, Conforti, Francesca Luisa, Aronica, Eleonora, Cavallaro, Sebastiano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6620285/
https://www.ncbi.nlm.nih.gov/pubmed/31292500
http://dx.doi.org/10.1038/s41598-019-46355-w